Sophie Shevick

The Shevick Group is currently accepting new graduate students. Apply here.


The synthesis of complex molecules with precise control over their connectivity and three-dimensional shape is fundamental to advances in medicine, materials, and agricultural science. Success in these areas depends on developing new and efficient methods in synthetic organic chemistry.

The Shevick Group pursues creative solutions toward the construction of complex molecules, such as natural products. We will employ unique reactivity ascribed to main-group elements, particularly silicon and sulfur, to develop new approaches in radical methodology and stereoselective synthesis. Drawing heavily from physical organic principles, we will develop new methods for selective carbon and heteroatom bond formation and apply them to the synthesis of stereochemically complex natural products and synthetically-useful building blocks. Students and researchers in the group will receive comprehensive training in synthetic organic chemistry, from fundamental physical organic principles to advanced laboratory technical expertise.

    Awards
  • 2022 - 2025 - NIH Ruth L. Kirschstein National Research Service Award (NRSA) Postdoctoral Fellow
  • 2019-2022 - NIH Translational Research for Doctoral Students (TL1) Fellow
  • 2018 - ARCS Scholar
  • 2017 - Turner B. Lesly Starr Shelton Scholarship
Recent Publications

“Asymmetric Syntheses of (+)- and (−)-Collybolide Enable Reevaluation of kappa-Opioid Receptor Agonism,” S.L. Shevick, S.M. Freeman, G. Tong, R.J. Russo, L.M. Bohn, R.A.Shenvi ACS Cent. Sci. 2022, 8, 948-954

“Catalytic hydrogen atom transfer to alkenes: a roadmap for metal hydrides and radicals,” S.L. Shevick, C.V. Wilson, S. Kotesova, D. Kim, P.L. Holland, R.A. Shenvi Chem. Sci. 2020, 11, 12401-12422

“Mechanistic Interrogation of Co/Ni-Dual Catalyzed Hydroarylation,” S.L.Shevick, C. Obradors, R.A. Shenvi J. Am. Chem. Soc. 2018, 140, 12056-12068