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Inorganic and Materials Chemistry, Metal-Organic Frameworks, Nanoparticle Assembly, Materials for Sustainable Energy
New materials drive innovations in energy, medicine, and countless other fields. We are broadly interested in the design, synthesis, and discovery of new materials. We use a suite of chemical building blocks, including small molecules, biomolecules, metal clusters, nanoparticles, etc., to construct well-ordered (periodic) hierarchical structures whose properties depend intrinsically on the nature of the building blocks and their organization in space. Ultimately, we strive toward the conception and realization of unifying design principles that will facilitate the organization of such building blocks over multiple length scales.
Given the multi-disciplinary nature of our research, students and postdocs from diverse chemical disciplines are encouraged to participate. While in lab, they become familiar with a wide array of solution, solid-state, automated, and high-throughput synthetic methods. Further, they become skilled at using NMR, mass spectroscopy, IR, SEM, TEM, thermal analysis, sorption, fluorescence spectroscopy and microscopy, and X-ray diffraction methods to characterize their materials. They are encouraged to attend national and international meetings to disseminate their most exciting results.
- Chancellor's Distinguished Research Award, 2014
- Kavli Fellow, 2012
- ChemComm Emerging Investigator, 2011
- NSF CAREER Award, 2010-2015
- US Delegate for Transatlantic Frontiers of Chemistry Conference, 2008
“Modulator approach for the design and synthesis of anisotropic multi-domain metal-organic frameworks”, Yiwen He, Zhehao Li, Zoe M. Soilis, Gefan He, Nathaniel L. Rosi, Chem. Sci., 2025, 16, 7442
“Crystallographic Visualization of Distinct Iodic Aggregations in Isostructural Metal–Organic Frameworks”, Yi Han, Yiwen He, Yin-Ke Fu, Hongliang Huang, Hongdong Li, Jiong-Peng Zhao, Lei Wang, Qian Niu, Nathaniel L. Rosi, J. Am. Chem. Soc. 2025, 147, 23, 19968–19975
“Leveraging Ligand Steric Demand to Control Ligand Exchange and Domain Composition in Stratified Metal-Organic Frameworks”, Yiwen He, Mattheus De Souza, Tian-Yi Luo, Siddarth K. Achar, J. Karl Johnson, Nathaniel L. Rosi, Angew. Chem. Int. Ed. 2024, 63, e202409150
“Imparting Stability to Chiral Helical Gold Nanoparticle Superstructures”, Yicheng Zhou, Yuyu Zhang, Nathaniel L. Rosi, Langmuir 2024, 40, 30, 15700–15709
“Zeolitic MOFs get a facelift,” N.L. Rosi*, P. Das Nat. Synth. 2024, 3, 5-6
“Ligand Chromophore Modification Approach for Predictive Incremental Tuning of Metal–Organic Framework Color,” Z.M. Soilis, T.H. Choi, J. Brennan, R.R. Frontiera, J.K. Johnson, N.L. Rosi* Chem. Mater. 2023, 35, 7741-7749
“Molecular Modulator Approach for Controlling the Length of Chiral 1D Single-Helical Gold Nanoparticle Superstructures,” Y. Zhang, S.C. Brooks, N.L. Rosi* Chem. Mater. 2023, 35, 5071-5078
“Implementation of a Core–Shell Design Approach for Constructing MOFs for CO2 Capture,” Y. He, P. Boone, A.R. Lieber, Z. Tong, P. Das, K.M. Hornbostel, C.E. Wilmer, N.L. Rosi* ACS Appl. Mater. Interfaces 2023, 15, 23337-23342
“Single Amino Acid Modifications for Controlling the Helicity of Peptide-Based Chiral Gold Nanoparticle Superstructures,” S.C. Brooks, R. Jin, V.C. Zerbach, Y. Zhang, T.R. Walsh*, N.L. Rosi* J. Am. Chem. Soc. 2023, 145, 6546-6553
“Crystallographic Mapping and Tuning of Water Adsorption in Metal–Organic Frameworks Featuring Distinct Open Metal Sites,” Y. Han*, P. Das, D.C. Sorescu, K.D. Jordan, N.L. Rosi* J. Am. Chem. Soc. 2022, 144, 19567-19575
“Leveraging Peptide Sequence Modification to Promote Assembly of Chiral Helical Gold Nanoparticle Superstructures,” S. Mokashi-Punekar, S.C. Brooks, C.D. Hogan, N.L. Rosi* Biochemistry 2021, 60, 1044-1049
“Ship-in-a-Bottle Preparation of Long Wavelength Molecular Antennae in Lanthanide Metal–Organic Frameworks for Biological Imaging,” P.F. Muldoon, G. Collet, S.V. Eliseeva, T.-Y. Luo, S. Petoud*, N.L. Rosi* J. Am. Chem. Soc. 2020, 142, 8776-8781
“Luminescence “Turn-On” Detection of Gossypol using Ln3+- Based Metal-Organic Frameworks and Ln Salts,” T.-Y. Luo, P. Das, D. L. White, C. Liu, A. Star, N. L. Rosi* J. Am. Chem. Soc. 2020, 142 6, 2897-2904
“Mixed Matrix Membranes from a Microporous Polymer Blend and Nanosized Metal–Organic Frameworks with Exceptional CO2/N2 Separation Performance,” P.F. Muldoon, S.R. Venna, D.W. Gidley, J.S. Baker, L. Zhu, Z. Tong, F. Xiang, D.P. Hopkinson, S. Yi*, A.K. Sekizkardes*, N.L. Rosi* ACS Materials Lett. 2020, 2, 821-828
“H2/CO2 separations in multicomponent metal-adeninate MOFs with multiple chemically distinct pore environments,” Z.M. Schulte, Y.H. Kwon, C. Liu, L. Li, Y. Yang, A. Gamble Jarvi, S. Saxena, G. Veser, J.K. Johnson, N.L. Rosi* Chem. Sci. 2020, 11, 12807-12815
“Designing open metal sites in metal-organic frameworks for paraffin/olefin separations,” M.H. Mohamed, Y. Yang, L. Li, S. Zhang, J.P. Ruffley, A Gamble Jarvi, S. Saxena, G. Veser, K. J. Johnson, N. Rosi, J. Am. Chem. Soc 2019, 141 13003
“Multivariate Stratified Metal–Organic Frameworks: Diversification Using Domain Building Blocks,” T.-Y. Luo, C. Liu, X.Y. Gan, P.F. Muldoon, N.A. Diemler, J.E. Millstone, N.L. Rosi* J. Am. Chem. Soc. 2019, 141, 2161-2168
“Tuning the Structure and Chiroptical Properties of Gold Nanoparticle Single Helices via Peptide Sequence Variation,” S. Mokashi-Punekar, T.R. Walsh*, N.L. Rosi* J. Am. Chem. Soc. 2019, 141, 15710-15716
“Construction of Chiral, Helical Nanoparticle Superstructures: Progress and Prospects,” S. Mokashi-Punekar, Y. Zhou, S.C. Brooks, N.L. Rosi Adv. Mater. 2019, 32, 1905975
“Programmable topology in new families of heterobimetallic metal-organic frameworks,” P.F. Muldoon, C. Liu, C.C. Miller, S.B. Koby, A.G. Jarvi, T.-Y. Luo, S. Saxena, M. O’Keeffe, N.L. Rosi, J. Am. Chem. Soc. 2018, 140, 6194
“Near infrared excitation and emission in rare earth MOFs via encapsulation of organic dyes† ,” C. Liu, S.V. Eliseeva, T.-Y. Luo, P.F. Muldoon, S. Petoud, N.L. Rosi* Chem. Sci. 2018, 9, 8099-8102
“Systematic adjustment of pitch and particle dimensions within a family of chiral plasmonic gold nanoparticle superstructures,” S. Mokashi-Punekar, A.D. Merg, and N.L. Rosi.* J. Am. Chem. Soc. 2017, 139, 15043-15048
“Rare earth pcu metal-organic framework platform based on RE4(m3-OH)4(COO)62+ clusters: rational design, directed synthesis, and deliberate tuning of excitation wavelengths,” T.Y. Luo, C. Liu, S.V. Eliseeva, P.F. Muldoon, S. Petoud*, and N.L. Rosi.* J. Am. Chem. Soc. 2017, 139, 9333-9340
“Peptide-directed assembly of single-helical gold nanoparticle superstructures exhibiting intense chiroptical activity,” A.D. Merg, J.C. Boatz, A. Mandal, G. Zhao, S. Punekar, C. Liu, Z. Wang, P. Zhang, P.C.A. van der Wel*, N.L. Rosi.* J. Am. Chem. Soc. 2016, 138, 13655-13663
“Establishing porosity gradients within metal-organic frameworks using partial postsynthetic ligand exchange,” C. Liu, C. Zeng, T.Y. Luo, A.D. Merg, R. Jin, N.L. Rosi.* J. Am. Chem. Soc. 2016, 138, 12045-12048
