Department of Chemistry



Prof. Lillian T. Chong and her research group have just published a paper in Nature Communications

March 5, 2018 - 8:10am

 "Large enhancement of response times of a protein conformational switch by computational design" was released for publication on March 9 in Nature Communications. The paper reports the enhancement of the kinetics of an engineered protein-based calcium sensor by >32-fold, bringing the response time of the sensor into the timescales of physiological calcium fluctuations. The primary author of the paper is an undergraduate in the Chong research lab, Alex DeGrave.

Link to publication