Department of Chemistry






Want to be part of a company whose goal is to provide outstanding pharmaceutical discovery and development services by creating and using cutting edge science and developing new methods and molecules? Do you want to work with some of the brightest minds in the industry in a rapidly growing company on a trajectory to have a major impact in the life science research arena? We are seeking a talented and passionate scientist who is eager to be part of our success, and who embraces our core values: Integrity, Excellence, and Teamwork. This role requires a highly driven and proactive scientist with a passion for drug development, the curiosity and flexibility to work on diverse projects, and the tenacity to tackle complex questions by developing/applying new methods to solve previously intractable problems in drug development in a dynamic, fast-paced, team-oriented and collaborative environment.


We require an experienced physical organic chemist with broad knowledge of and significant hands on experience with small molecule analytical technology including chromatographic and physical characterization methods.  This individual will plan and execute experiments in physicochemical analysis and structural characterization.




  • Evaluate physicochemical properties of small molecules relevant to drug development and subsequently communicate the interpretation and implication of results to clients.

  • Develop analytical methods and characterize product variants

  • Execute and oversee specialized analytical testing and generation of technical documents

  • Maintain a strong awareness of current scientific literature, particularly in the area of drug substance characterization, and actively apply new concepts as appropriate.

  • Design experiments to develop pre-clinical and clinical formulations of drug candidates to support drug discovery and development.

  • Design experiments to determine the stability in prototype clinical formulations, to detect and identify the decomposition products, and to achieve formulations with acceptable shelf-life.

  • Perform laboratory experiments related to the above.

  • Create presentations for outside scientific meetings and conferences to showcase Wolfe Laboratories’ scientific leadership in the field of small molecule analysis and characterization.

  • Interface with clients to develop an in-depth understanding of client objectives and define solutions to meet their program requirements

  • Develop compelling approaches and solutions to address client needs

  • Write persuasive proposals for the projects

  • Regularly interact with clients to keep them abreast of project progress

  • Write and review interim and final reports.




At Wolfe Laboratories Inc., we pride ourselves on retaining and growing our team members, and ensuring they are developing to their full potential. This position can provide many different avenues for advancement, including:


  • Training towards becoming a Project Manager
  • Leader of an innovative business line
  • Become a Lead Technical Researcher
  • Managing a team of Postdoctoral employees




  • Ph.D. in Physical Organic Chemistry, Pharmaceutical Chemistry, Medicinal Chemistry, Process Chemistry, Chemical Engineering, or closely related discipline

  • In depth expertise in physical organic chemistry and the structural characterization of small molecules as they relate to the pre-formulation and formulation development of new drugs

  • Expertise in the field of physicochemical analysis and structural characterization

  • Hands-on experience with method development as well as analytical methods used for physicochemical characterization of pharmaceutical products such as spectroscopy and HPLC analysis.

  • A demonstrated drive to apply technical knowledge to developing drug formulations

  • Established track record of significant contributions as an individual technical expert as well as a leader of small teams

  • Outstanding written and oral communicationskills as well as polished and persuasive client presentation skills



  • Capability with DSC, TGA, and/or lyophilization

  • Experience in creating and deliveringtrainings


Interested candidates are requested to email a copy of their resume with a cover letter and unofficial transcripts to:



Wolfe Labs’ employees are innovators with a winning attitude. We offer a fun, multi-cultural environment and value teamwork and accountability through a results-oriented, customer-centric focus. We provide generous health and financial benefits, learning opportunities, competitive compensation, the potential to participate in our employee stock option plan, and a wide range of work/life benefits. Candidates who are keen experimentalists, independent thinkers and enthusiastic team players that have a passion for drug development are encouraged to apply.


For more information, visit us at:


Wolfe Laboratories, Inc. is an Equal Employment Opportunity employer.