Sunil Saxena

      The research of Professor Sunil Saxena's group is featured in the March 28^th edition of the C&EN on page 61. The article describes developments in electron spin resonance methodology that enable the measurement of global folding patterns in membrane proteins and amyloids. These proteins pose significant challenges to established methods like crystallography and NMR. Recent FT-ESR results obtained by his group members Katherine Stone and Marco Bonora, in collaboration with Professor Mike Cascio, on the Glycine Receptor a ~250 kDa membrane bound ion channel complex are highlighted.

Intersubunit proximities in the Glycine Receptor are "imaged" by spin labeling and FT ESR distance measurements